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齐向辉

148DB

个人简介

姓名

齐向辉

性别

出生日期

----

职称

教授 博导

电话

+86-139****2912

传真

+86-511-88780201

Email

qxh@ujs.edu.cn

详细介绍

【学术简介】

齐向辉,十大外围足彩网站教授、博士生导师,微生物生物合成与智能制造团队负责人,江苏省“六大人才高峰”高层次人才,福建省“闽江学者”特聘讲座教授。主要研究方向为高附加值化学品的微生物合成与制造,重点在功能微生物的筛选鉴定与工程菌开发、新酶挖掘与酶的定向进化和理性设计、底盘细胞设计与改造、微生物组学、生物转化与合成、发酵工程与工艺优化、代谢途径工程与分子机制解析、纳米酶与纳米生物工程、益生菌/益生元与功能等方面开展了一系列的研究工作。主持国家重点研发计划、NSFC国际合作等国家级课题多项;发表论文150余篇,以第一/通讯作者在Renew Sust Energ Rev(IF=15.0,2篇)、Trends Food Sci Tech(IF=12.6)、Sci Bull(IF=11.8,2篇)、Energ Convers Manage(IF=9.7)、ACS Sustain Chem Eng(IF=8.2)、 Bioresource Technol(IF=9.6,9篇)、J Clean Prod(IF=9.3)、Food Chem(IF=7.5)、J Environ Manage(IF=6.8)、Mol Nutr Food Res (IF=5.9)、J Agr Food Chem(IF=5.3,4篇)等期刊发表SCI论文52篇,EI论文16篇;第一/通讯作者累计影响因子>325分(篇均>6.25分),JCR Q1区论文41篇,高被引论文5篇、热点论文1篇;另外,合作发表IF>12以上Renew Sust Energ Rev(IF=15.0)1篇、Compr Rev Food Sci F(IF=12.8)1篇;主编Elsevier英文专著1部,参编Springer Nature、Elsevier等中英文专著5部;申请专利(含PCT)20余件;获江苏省级各类成果一等奖1项、二等奖2项,获江苏省优秀研究生毕业论文指导教师奖1项,获足球外围最靠谱的平台优秀教师、优秀研究导师等多项荣誉称号;担任40多个SCI期刊的评审专家、多个国际期刊主编或编委,担任国家重点研发计划/专项、NSFC、智利国家科技发展基金(FONDECYT)、印度(MALVIYA),以及多省市的基金评审专家;担任高新技术企业评审专家。

学习经历:

2016-2017 美国耶鲁大学,交流;

2015-2016 美国加州大学洛杉矶分校, 访问学者;

2009-2011 南京工业大学 化学工程与技术 博士后;

2003-2006 广西大学亚热带农业生物资源保护与利用国家重点实验室 微生物学 博士;

研究经历:

2016-至今 足球外围最靠谱的平台 教授、博导;

2013-2014 江苏省镇江市京口区政府、中储粮镇江基地总经理助理;

2010-2016 足球外围最靠谱的平台 副教授;

2007-2010 足球外围最靠谱的平台 讲师;

1998-2000 河北省元氏环保局 工程师;

学术社会兼职及荣誉:

入选江苏省“六大人才高峰”高层次人才,福建省“闽江学者”特聘讲座教授,科学中国人环境与轻纺领域2018年度人物提名人;担任国际期刊Canadian Journal of Applied Sciences的Editor in Chief,担任国际期刊Current Biotechnology、International Journal of Food Science and Biotechnology、Biotechnology Frontier等的Editor Board;担任Renew Sust Energ Rev(IF=15.0)、Protein & Cell(IF=14.9)、ACS Catalysis(IF=13.1)、Critical Reviews in Food Science and Nutrition(IF=11.2)、Energ Convers Manage(IF=9.7)、J Clean Prod(IF=9.3)、Crit Rev Biotechnol(IF=8.4)、Chemosphere(IF=7.1)、J Ind Eng Chem(IF=6.1)、Cancer Sci(IF=6.7)、Food Research International(IF=6.5)、Int J Hydrogen Energ(IF=5.8)、Industrial Crops & Products (IF=5.6)、J Agr Food Chem(IF=5.3)、、Microbiol Res(IF=5.4)、Int J Food Microbiol (IF=5.3)、LWT-Food Sci Technol(IF=5.0)、Biomass Convers Bior(IF=5.0)Molecular Catalysis(IF=5.1)、Appl Microbiol Biot(IF=4.8)、Front Env Sci Eng(IF=4.4)、Environ Sci Pollut R(IF=4.2)、Journal of Polymers and the Environment(IF=3.7)、Enzyme Microb Tech(IF=3.5)、Bioprocess and Biosystems Engineering(IF=3.2)、J Biosci Bioeng(IF=2.9)、Appl Biochem Biotech(IF=2.9)、Mol Biotechnol(IF=2.7)、Biotechnol Lett(IF=2.5)、Journal of Basic Microbiology(IF=2.3)、Preparative Biochemistry & Biotechnology(IF=2.2)、Folia Microbiol(IF=2.1)、Chem Pap(IF=2.1)、Appl Biol Chem(IF=1.8)、BioResources(IF=1.6)等40多个SCI期刊的Reviewer;担任Frontiers in Bioengineering and Biotechnology(IF=5.89)、Frontiers in Molecular Biosciences(IF=5.246)、Frontiers in Materials(IF=3.515)的 Review Editor;担任高新技术企业、国家重点研发计划/专项、NSFC、智利国家科技发展基金(FONDECYT)、印度(MALVIYA),以及多省市的基金评审专家。

【主讲课程】

微生物学、酶工程、生化工程、合成生物学、基因工程、食品生物技术前沿进展(中文、英文)等

【指导硕、博士生研究方向】

博士研究生:

1、微生物生物合成与智能制造;2、微生物发酵工程、途径工程与生物合成;3、分子酶工程与生物催化;4、益生菌与益生元的开发、功能与应用;5、生物纳米工程

硕士研究生:

1、微生物生物合成与智能制造;2、微生物发酵工程、途径工程与生物合成;3、 分子酶工程与生物催化;4、益生菌与益生元的开发、功能与应用;5、生物纳米工程

【研究领域】

致力于以五碳糖、六碳糖、甘油以及生物质等为原料的功能性糖醇等高附加值食品与食品添加剂、医药等产品的生物合成与制造的基础、开发、应用等方面的研究工作。重点围绕D-阿拉伯糖醇、木糖醇、D-塔格糖、D-阿洛糖、D-阿洛酮糖、3-羟基丙酸、1,3-丙二醇、生物乙醇等高附加值食品、医药等化学品与平台化合物,开展功能微生物的筛选鉴定与工程菌开发、新酶挖掘与酶的定向进化和理性设计、底盘细胞设计与改造、微生物组学、生物转化与合成、发酵工程与工艺优化、代谢途径工程与分子机制解析、纳米酶与纳米生物、益生菌/益生元与功能等方面的研究;并致力于高附加值食品与食品添加剂、医药、化学品等相关产品的应用开发、功能与产业化。同时,开展了食源性微生物的防控等方面的研究工作。

***Excellent PhDs (Age≤35), especially with microbial biosynthesis background, are warmly welcome for applying related Positions in our lab! Excellent postgraduate students with the background of Synthetic biology, Microbiology and Genetic engineering are welcome as well! ***

https://www.x-mol.com/groups/Qi_Xianghui(Personal Homepage)

http://smkx.ujs.edu.cn/info/1037/4548.htm; (School of Life Science)

https://www.researchgate.net/profile/Xianghui_Qi;(ResearchGate)

https://www.mendeley.com/profiles/xianghui-qi/;(Mendeley)

【主要论著】

发表论文150余篇,以第一或通讯作者在Renew Sust Energ Rev(IF=15.0,2篇)、Trends Food Sci Tech(IF=12.6)、Sci Bull(IF=11.8,2篇)、Energ Convers Manage(IF=9.7)、ACS Sustain Chem Eng(IF=8.2)、Bioresource Technol(IF=9.6,9篇)、J Clean Prod(IF=9.3)、Food Chem(IF=7.5)、J Environ Manage(IF=6.8)、Mol Nutr Food Res(IF=5.9)、J Agr Food Chem(IF=5.3,4篇)等期刊发表SCI论文52篇,EI论文16篇,累计影响因子>325分(篇均>6.25分),JCR Q1区论文41篇,高被引论文5篇、热点论文1篇;合作发表IF>9以上Renew Sust Energ RevIF=15.0)1篇、Compr Rev Food Sci FIF=12.8)1篇、Sep Purif Rev(IF=9.61篇;主编Elsevier英文专著1部(Nanomaterials for Bio-Catalysis),参编Springer Nature、Elsevier等中英文专著5部。

2021年代表性论文(2020,IF):

[1] Yuvaraj R, Lakshmi N P, Guoyan Zhang, JunhuaYun, Xianghui Qi (*). Harnessing l-arabinose isomerase for biological production of D-tagatose: Recent advances and its applications, Trends in Food Science & Technology, 2021, 107:16-30. dio:10.1016/j.tifs.2020.11.020. (SCI,JCR Q1,中科院一区, IF=12.563)

[2] Junhua Yun, Hossain M. Zabed, Yufei Zhang, Amreesh Parvez, Guoyan Zhang, Xianghui Qi (*). Co-fermentation of glycerol and glucose by a co-culture system of engineered Escherichia coli strains for 1,3-propanediol production without vitamin B12 supplementation. Bioresource Technology, 2021, 319: 124218. doi:10.1016/j.biortech.2020.124218. (SCI,JCR Q1,中科院一区, IF=9.642)

[3] Yufei Zhang, Hossain M. Zabed, Junhua Yun, Guoyan Zhang, Yang Wang, Xianghui Qi (*). Notable improvement of 3-hydroxypropionic acid and 1,3-propanediol co-production using modular co-culture engineering and pathway rebalancing. ACS Sustainable Chemistry & Engineering, 2021,9:4625-4637. Online. dio:10.1021/acssuschemeng.1c00229 (JCR Q1,中科院一区, IF=8.198)

[4] Xiaolan Li, Z. Zhang, H. Zabed, Junhua Yun, Guoyan Zhang, Xianghui Qi*. An insight into the roles of dietary tryptophan and its metabolites in intestinal inflammation and inflammatory bowel disease. Molecular Nutrition & Food Research, 2021, 65(5):e2000461. dio:10.1002/mnfr.202000461. (SCI,JCR Q1,中科院一区, IF=5.914)

[5] Radhika Chandankere, Yuvaraj Ravikumar, Hossain M. Zabed, Poorna Chandrika Sabapathy, Junhua Yun, Guoyan Zhang, Xianghui Qi (*). Conversion of agroindustrial wastes to rhamnolipid by Enterobacter sp. ujs-rc and its role against biofilm forming foodborne pathogen. Journal of Agricultural and Food Chemistry, 2020, 68(52): 15478-15489. dio:10.1021/acs.jafc.0c05028 (SCI,JCR Q1,中科院一区, IF=5.279)

[6] Yifeng Zhang#, Herui Gao#, Xianghui Qi#, Song Gao, Shumin Xu, Hongling Wang, Yingfeng An. Efficient molecular biological manipulations with improved strategies based on novel Escherichia coli vectors. Journal of Agricultural and Food Chemistry, 2021, 69:5086-5095. (SCI,JCR Q1,中科院一区, IF=5.279)

[7] Ernest Fokum, Hossain M. Zabed, Yuvaraj Ravikumar, Mostafa E. Elshobary, Radhika Chandankere, Yufei Zhang, Junhua Yun, Xianghui Qi (*). Co-fermentation of glycerol and sugars by Clostridium beijerinckii: An appealing strategy for enhancing the biosynthesis of 1,3-propanediol, Food Bioscience, 2021,41: 101028. (SCI,JCR Q1,中科院二区, IF=4.240)

[8] Jiao Yuan, Yuvaraj Ravikumar, Guoyan Zhang, Junhua Yun, Yufei Zhang, Hossain M. Zabed, Xianghui Qi (*). L-arabinose isomerase from Lactobacillus parabuchneri and its whole cell biocatalytic application in D-tagatose biosynthesis from D-galactose. Food Bioscience, 2021, 41: 101034. doi:10.1016/j.fbio.2021.101034. (SCI,JCR Q1,中科院二区, IF=4.240)

[9] Marian Rofeal, Fady Abd El-Malek, Xianghui Qi (*). In vitro assessment of green polyhydroxybutyrate/chitosan blend loaded with kaempferol nanocrystals as a potential dressing for infected wounds. Nanotechnology, 2021, 32:375102. doi:10.1088/1361-6528/abf7ee. (SCI,JCR Q1,中科院二区, IF=3.874)

[10] Yifeng Zhang#, Xianghui Qi#, Shuo Yao, Song Gao, Shumin Xu, Hongling Wang, Xia Liu, Yingfeng An. Construction of novel curdlan-based and Ca2+-chelated magnetic microspheres (CCMM) for efficient protein purification and oriented immobilization. Enzyme and Microbial Technology, 2021,148: 109802. (SCI,JCR Q1,中科院二区, IF=3.493)

[11] Gihan M. El-Khodary, Heba S. El-Sayed, Hanan M. Khairy, Mohamed A. El-Sheikh, Xianghui Qi (*), Mostafa E. Elshobary. Comparative study on growth, survival and pigmentation of Solea aegyptiaca larvae by using four different microalgal species with emphasize on water quality and nutritional value. Aquaculture Nutrition, 2021,27:615-629. doi: 10.1111/anu.13211. (SCI,JCR Q1,中科院二区, IF=3.497)

[12] Mostafa E. Elshobary, Hossain M. Zabed, Junhua Yun, Guoyan Zhang, Xianghui Qi (*). Recent insights into microalgae-assisted microbial fuel cells for generating sustainable bioelectricity. International Journal of Hydrogen Energy, 2021, 46(4):3135-3159. doi:10.1016/j.ijhydene.2020.06.251 (SCI,JCR Q1,中科院二区, IF=5.816, Highly Cited Paper)

[13] Muhammad Waheed Iqbal, Tahreem Riaz, Iqra Yasmin, Ali Ahmad Leghari, Sabahat Amin, Muhammad Bilal, Xianghui Qi (*). Chitosan-Based Materials as Edible Coating of Cheese: A Review. Starch-Starke, 2021 (SCI,JCR Q2, 中科院三区, IF=2.741)

[14] Shumin Xu#, Xianghui Qi#, Song Gao, Yifeng Zhang, Hongling Wang, Yilun Shao, Yao Yang, Yingfeng An. Modification of DNA regions with metagenomic DNA fragments (MDRMDF): A convenient strategy for efficient protein engineering. Biochimie, 2021. (SCI,JCR Q2, 中科院三区, IF=4.079)

[15] E. Fokum, H. M. Zabed, J. Yun, G. Zhang, X. Qi (*). Recent technological and strategical developments in the biomanufacturing of 1,3-propanediol from glycerol. International Journal of Environmental Science and Technology, 2021, doi: 10.1007/s13762-020-03036-w. (SCI,JCR Q1, 中科院四区, IF= 2.860)

[16] Poorna C S, Sabarinathan D, Parthiban A, Amreesh P, Preethi K, Xianghui Qi(*). Active polyhydroxybutyrate (PHB)/sugarcane bagasse fiber-based anti-microbial green composite: material characterization and degradation studies. Applied Nanoscience, 2021, DOI:10.1007/s13204-021-01972-8 (SCI,JCR Q1, 中科院三区, IF= 3.674)

[17] Jahidul Islam, Faisal I Chowdhury*, Wahidur R, Xianghui Qi, M. Rezaur Rahman, Jagotamoy Das, Jamal Uddin, Hossain M. Zabed*. Toward polymer composites based and architectural engineering induced flexible electrodes for lithium-ion batteries. Renewable and Sustainable Energy Reviews, 2021, 148: 111302. (SCI,JCR Q1,中科院一区, IF=14.982)

[18] Xiaolan Li, Zhi-Hong Zhang, Xianghui Qi, Lin Li, Jie Zhu, Charles S. Brennan*, Jing-Kun Yan*. Application of non-thermal processing technologies in extracting and modifying polysaccharides: A critical review. Comprehensive Reviews in Food Science and Food Safety, 2021. (SCI,JCR Q1,中科院一区, IF=12.811)

[19] J. N. Sahu*, Rama Rao Karri, Hossain M. Zabed, Shahriar Shams, Xianghui Qi. Current Perspectives and Future Prospects of Nano-Biotechnology in Wastewater Treatment. Separation & Purification Reviews, 2021, 50: 139-158. doi: 10.1080/15422119.2019.1630430. (SCI,JCR Q1,中科院一区, IF=9.636)

2020年代表性论文(2020,IF):

[1] Hossain M Z, Suely A, Junhua Yun, Guoyan Zhang, Yufei Zhang, Xianghui Qi (*). Biogas from microalgae: Technologies, challenges and opportunities. Renew Sust Energ Rev, 2020, 117: 109503. doi: 10.1016/j.rser.2019.109503. (SCI,JCR Q1,中科院一区, IF=14.982, Highly Cited Paper)

[2] Suely Akter, Hossain M. Zabed, J.N. Sahu, F. I. Chowdhury, G. Faruq, A.N. Boyce, Xianghui Qi (*). Bioethanol production from water-soluble and structural carbohydrates of normal and high sugary corn stovers harvested at three growth stages. Energy Conversion and Management, 2020, 221: 113104. doi.org/10.1016/j.enconman.2020.113104. (SCI,JCR Q1,中科院一区, IF=9.709)

[3] Guoyan Zhang, Hossain M. Zabed, Junhua Yun, Jiao Yuan, Yufei Zhang, Yang Wang, Xianghui Qi (*). Two-stage biosynthesis of D-tagatose from milk whey powder by an engineered Escherichia coli strain expressing L-arabinose isomerase from Lactobacillus plantarum. Bioresource Technology, 2020, 305:123010. doi: 10.1016/j.biortech.2020.123010. (SCI,JCR Q1,中科院一区, IF=9.642)

[4] Poorna C S, Sabarinathan D, Katharina M, Parthiban A, Preethi K, Yuvaraj R, Hossain M Z, Xianghui Qi (*). Recent developments in Polyhydroxyalkanoates (PHAs) production–A review. Bioresource Technology, 2020, 306:123132. doi: 10.1016/j.biortech.2020.123132. (SCI,JCR Q1,中科院一区, IF=9.642, Highly Cited Paper)

[5] Wang Yang, Yuvaraj Ravikumar, Guoyan Zhang, Junhua Yun, Yufei Zhang, Amreesh Parvez, Xianghui Qi (*), Wenjing Sun*. Biocatalytic synthesis of D-allulose using novel D-tagatose 3-epimerase from Christensenella minuta. Frontiers in Chemistry, 2020, 8:622325. doi: 10.3389/fchem.2020.622325. (SCI,JCR Q2,中科院二区, IF=5.221)

[6] Guoyan Zhang, Yingfeng An, Amreesh Parvez, Hossain M. Zabed, Junhua Yun, Xianghui Qi (*). Exploring a highly D-galactose specific L-Arabinose isomerase from Bifidobacterium adolescentis for D-tagatose production. Frontiers in Bioengineering and Biotechnology, 2020, 8: 377. doi: 10.3389/fbioe.2020.00377. (SCI,JCR Q1,中科院二区, IF=5.890)

[7] Radhika C, Jayabaskaran C, Kamalraj S, Vanitha C. S, Amreesh P, Hossain M Z, Yogesh C S, Xianghui Qi (*). Pleiotropic functions and biological potentials of silver nanoparticles synthesized by an endophytic fungus. Frontiers in Bioengineering and Biotechnology, 2020, 8:95. doi:10.3389/fbioe.2020.00095. (SCI,JCR Q1,中科院二区, IF=5.890)

[8] Mostafa E E, Rania A El-S, MohamedA, Hossain M Z, Xianghui Qi (*), Antimicrobial and antioxidant characterization of bioactive components from Chlorococcum minutum. Food Bioscience, 2020, 35: 100567. dio: 10.1016/j.fbio.2020.100567. (SCI,JCR Q1,中科院二区, IF=4.240, Highly Cited Paper)

[9] Elshobary, M.E., Essa, D.I., Attiah, A.M., Salem Z.E., Xianghui Qi (*). Algal community and pollution indicators for the assessment of water quality of Ismailia canal, Egypt. Stoch Environ Res Risk Assess 2020, 34:1089–1103. doi: 10.1007/s00477-020-01809-w. (SCI,JCR Q1,中科院二区, IF=3.379)

[10] Miaomiao Yang, Hossain M. Zabed, Junhua Yun, Guoyan Zhang, Xianghui Qi (*). The draft genome sequence of Clostridium butyricum QXYZ514, a potent bacterium for converting glycerol into fuels and bioproducts in the waste-based biorefinery, Current Microbiology, 2020, 77(11),3371-3376. doi: 10.1007/s00284-020-02182-1. (SCI,JCR Q3,中科院四区, IF=2.188)

[11] Amreesh Parvez, Sunita Yadav, Vivek Pandey, Xianghui Qi (*). In Silico high-throughput virtual screening and molecular dynamics simulation study to identify 3CLpro inhibitor of COVID-19. Research Square, 2020, doi: 10.21203/rs.3.rs-29546/v1.

[12] Suely Akter, Hossain M. Zabed, Munira Nasiruddin, Xianghui Qi (*). Piscicidal Effects of Terminalia arjuna Leaf, Bark and Fruit Extract on a Fresh Water Predatory Catfish, Heteropneustes fossilis. Research in Ecology. 2020, 02:44-48. doi: https://doi.org/10.30564/re.v2i1.1328.

2019年代表性论文(2020,IF):

[1] Hossain M Z, Suely A, Junhua Yun, Guoyan Zhang, Faisal N A, Xianghui Qi (*), and J. N. Sahu. Recent advances in biological pretreatment of microalgae and lignocellulosic biomass for biofuel production. Renew Sust Energ Rev, 2019, 105: 105-128. doi: 10.1016/j.rser.2019.01.048. (SCI,JCR Q1,中科院一区, IF=14.982, Highly Cited Paper, Hot Paper)

[2] Miaomiao Yang, Yingfeng An, Hossain M Z, Qi Guo, Junhua Yun, Guoyan Zhang, Faisal N A, Wenjing Sun, Xianghui Qi (*). Random mutagenesis of Clostridium butyricum strain and optimization of biosynthesis process for enhanced production of 1,3-propanediol. Bioresource Technology, 2019, 284: 188-196. doi: 10.1016/j.biortech.2019.03.098. (SCI,JCR Q1,中科院一区, IF=9.642)

[3] Hossain M Z, Yufei Zhang, Qi Guo, Junhua Yun, Miaomiao Yang, Guoyan Zhang, Xianghui Qi (*). Co-biosynthesis of 3-hydroxypropionic acid and 1,3-propanediol by a newly isolated Lactobacillus reuteri strain during whole cell biotransformation of glycerol, Journal of Cleaner Production, 2019, 226: 432-442. doi:10.1016/j.jclepro.2019.04.071. (SCI,JCR Q1,中科院一区, IF=9.297)

[4] Qi Guo, H. Zabed, Huanhuan Zhang, Xu Wang, JunhuaYun, Guoyan Zhang, MiaomiaoYang, Wenjing Sun, Xianghui Qi (*). Optimization of fermentation medium for a newly isolated yeast strain (Zygosaccharomyces rouxii JM-C46) and evaluation of factors affecting biosynthesis of D-arabitol. LWT-Food Science and Technology, 2019, 99: 319-327. doi:10.1016/j.lwt.2018.09.086. (SCI,JCR Q1,中科院一区, IF=4.952)

[5] Xia Liu#, Xianghui Qi#, Song Zhu, Bo Jiang, Song Gao, YifengZhang, Hongling Wang, Shumin Xu, Yifei Liu, Yingfeng An. Embedding inulin fructotransferase from Arthrobacter aurescens into novel curdlan-based mesoporous silica microspheres for efficient production of Difructose Anhydride III. Food Chemistry, 2019, 299: 125128. doi:10.1016/j.foodchem.2019.125128. (SCI,JCR Q1,中科院一区, IF=7.514)

[6] Mostafa E E, Atef M A-S, Hanan M K, Dorya E, Hossain M Z, Xianghui Qi (*). Abd El-Fatah Abomohra. Influence of nutrient supplementation and starvation conditions on the biomass and lipid productivities of Micractinium reisseri grown in wastewater for biodiesel production. Journal of Environmental Management, 2019, 250: 109529. doi:10.1016/j.jenvman.2019, 109529. (SCI,JCR Q1,中科院二区, IF=6.789)

[7] Fokum, Ernest, Hossain M. Zabed, Qi Guo, Junhua Yun, Miaomiao Yang, Hao Pang, Yingfeng An, Wen Li, Xianghui Qi (*). Metabolic engineering of bacterial strains using CRISPR/Cas9 systems for biosynthesis of value-added products. Food Bioscience. 2019, 28: 125-132. doi: 10.1016/j.fbio.2019.01.003. (SCI,JCR Q1,中科院二区, IF=4.240)

[8] Guoyan Zhang, Yingfeng An, H. Zabed, Qi Guo, Jiao Yuan, Wenjing Sun, Xianghui Qi (*). Bacillus subtilis spore surface display technology: A review of its development and applications. Journal of Microbiology and Biotechnology, 2019, 29: 179-190. doi: 10.4014/jmb.1807.06066. (SCI,JCR Q2,中科院四区, IF=2.351)

[9] Wen Li, Zhicheng Zhou, Jiaxiang Huang, Guoyan Zhang, Faisal N A, Radhika C, Qi Guo, Xianghui Qi (*). Screening and identification of lactic acid bacteria with D-tagatose production capability. Biotechnology Journal International, 2019, 23: 1-6. doi: 10.9734/BJI/2019/v23i230074.

2018年代表性论文(2020,IF):

[1] Huanhuan Zhang, Junhua Yun, H. Zabed, Miaomiao Yang, Guoyan Zhang, Yilin Qi, Qi Guo, Xianghui Qi (*). Production of xylitol by expressing xylitol dehydrogenase and alcohol dehydrogenase from Gluconobacter thailandicus and co-biotransformation of whole cells. Bioresource Technology, 2018, 257:223-228. doi: 10.1016/j.biortech.2018.02.095. (SCI,JCR Q1,中科院一区, IF=9.642)

[2] Tinashe AM, H. Zabed, Miaomiao Yang, Junhua Yun, Huanhuan Zhang, Xianghui Qi (*). Improvement of industrially important microbial strains by genome shuffling: Current status and future prospects. Bioresource Technology, 2018, 257:281-289, doi: 10.1016/j.biortech.2018.02.118. (SCI,JCR Q1,中科院一区, IF=9.642)

[3] Qi Guo,Yingfeng An, Junhua Yun; Miaomiao Yang, Tinashe A M, Jingfei Zhu, Yanbo Xue, Yilin Qi, Zabed H, Wenjing Sun, Xianghui Qi (*). Enhanced D-tagatose production by spore surface-displayed L-arabinose isomerase from isolated Lactobacillus brevis PC16 and biotransformation. Bioresource Technology, 2018,247:940-946. doi:10.1016/j.biortech.2017.09.187. (SCI,JCR Q1,中科院一区, IF=9.642)

[4] Junhua Yun, Miaomiao Yang, Tinashe A M, Huanhuan Zhang, Yanbo Xue, Guoyan Zhang, Xianghui Qi (*), Wenjing Sun. Production of 1,3-propanediol using a novel 1,3-propanediol dehydrogenase from isolated Clostridium butyricum and co-biotransformation of whole cells. Bioresource Technology, 2018, 247:838-843. doi: 10.1016/j.biortech.2017.09.180. (SCI,JCR Q1,中科院一区, IF=9.642)

[5] Herui Gao#, Xianghui Qi#, Darren J. Hart, Song Gao, Hongling Wang, Shumin Xu, Yifeng Zhang, Xia Liu, Yifei Liu, Yingfeng An. Three novel Escherichia coli vectors for convenient and efficient molecular biological manipulations. Journal of Agricultural and Food Chemistry, 2018, 66, 6123−6131. doi: 10.1021/acs.jafc.8b01960. (SCI,JCR Q1,中科院一区, IF=5.279)

[6] Miaomiao Yang, Junhua Yun, Huanhuan Zhang, Guoyan Zhang, H. Zabed, Xianghui Qi (*). Bottlenecks and modification strategies of 1,3-propanediol biosynthesis from glycerol. Chinese Journal of Biotechnology, 2018, 34(7): 1069-1080. doi: 10.13345/j.cjb.170516. (PubMed)

[7] Miaomiao Yang, Junhua Yun, Huanhuan Zhang, Tinashe A M, H. Zabed, Yanbo Xue, Ernest Fokum, Wenjing Sun, Xianghui Qi (*). Genetically engineered strains: Application and advances for 1,3-propanediol production from glycerol, Food Technology and Biotechnology, 2018.56(1): 3-15. doi: 10.17113/ftb.56.01.18.5444. (SCI,JCR Q1,中科院三区, IF=3.918)

2017年前10篇代表性论文(2020,IF):

[1] Xianghui Qi (*), Huanhuan Zhang, Tinashe A M, Yingfeng An, Junhua Yun, Miaomiao Yang, Yanbo Xue, Shuhua Liang, Wenjing Sun, Zheng Cao. Improved xylitol production by expressing a novel D-arabitol dehydrogenase from isolated Gluconobacter sp. JX-05 and co-biotransformation of whole cells. Bioresource Technology, 2017, 235: 50-58. doi: 10.1016/j.biortech.2017.03.107. (SCI,JCR Q1,中科院一区, IF=9.642)

[2] Song Gao#, Xianghui Qi#, Darren J. Hart, Herui Gao, Yingfeng An, Expression and Characterization of Levansucrase from Clostridium acetobutylicum. Journal of Agricultural and Food Chemistry, 2017, 65 (4), 867-871. doi: 10.1021/acs.jafc.6b05165. (SCI,JCR Q1,中科院一区, IF=5.279)

[3] Xianghui Qi (*), Jing-Fei Zhu, Jun-Hua Yun, Jing Lin, Yi-Lin Qi, Qi Guo, Hong Xu. Enhanced xylitol production: Expression of xylitol dehydrogenase from Gluconobacter oxydans and mixed culture of resting cell. Journal of Bioscience and Bioengineering, 2016, 122 (3): 257-262. doi: 10.1016/j.jbiosc.2016.02.009. (SCI,JCR Q2,中科院三区, IF=2.894)

[4] Xianghui Qi (*), Junhua Yun, Yilin Qi, Huanhuan Zhang, Fei Wang, Qi Guo, Zheng Cao. Expression and characterization of a novel 1,3-propanediol dehydrogenase from Lactobacillus brevis. Applied Biochemistry and Biotechnology, 2016, 179:959-972. doi: 10.1007/s12010-016-2043-6. (SCI,JCR Q2,中科院三区, IF=2.926)

[5] Xianghui Qi (*), Yan Luo, Xu Wang, Jingfei Zhu, Jing Lin, Huanhuan Zhang, Fang Chen, Wenjing Sun. Enhanced D-arabitol production by Zygosaccharomyces rouxii JM-C46: isolation of strains and process of repeated-batch fermentation. Journal of Industrial Microbiology & Biotechnology, 2015, 42:807-812. doi: 10.1007/s10295-015-1603-z. (SCI,JCR Q2,中科院三区, IF=3.346)

[6] Xianghui Qi (*), Xu Wang, Jing Lin, Jingfei Zhu, Yan Luo, Wenying Deng, Fei Wang, Wenjing Sun, Jianzong Meng. Microbial and enzymatic process for production of xylitol from d-glucose. Current Organic Chemistry, 2014, 18(24):3131-3135. doi: 10.2174/138527281824150119095755. (SCI,JCR Q2,中科院二区, IF=2.180)

[7] Xianghui Qi (*), Wenying Deng, Fei Wang, Qi Guo, Huayou Chen, Liang Wang, Xiang He, Ribo Huang. Molecular Cloning, Co-expression, and Characterization of Glycerol Dehydratase and 1,3-Propanediol Dehydrogenase from Citrobacter freundii. Molecular Biotechnology,2013, 54(2):469-474. doi: 10.1007/s12033-012-9585-9. (SCI,JCR Q2,中科院四区, IF=2.695)

[8] Xianghui Qi (*), Qi Guo, Yuotuo Wei, Hong Xu, Ribo Huang. Enhancement of pH stability and activity of glycerol dehydratase from Klebsiella pneumoniae by rational design. Biotechnology Letters, 2012, 34:339-346. doi: 10.1007/s10529-011-0775-5. (SCI,JCR Q2,中科院三区, IF=2.461)

[9] Xianghui Qi, Yunlai Chen, Ke Jiang, Wenpu Zuo, Zhaofei Luo, Yutuo Wei, Liqin Du, Hang Wei, Ribo Huang (*), Qishi Du. Saturation-mutagenesis in two positions distant from active site of a Klebsiella pneumoniae glycerol dehydratase identifies some highly active mutants. Journal of Biotechnology, 2009, 144: 43-50. doi: 10.1016/j.jbiotec.2009.06.015.(SCI,JCR Q1,中科院三区, IF=3.307)

[10] QI Xianghui, SUN Liang, LUO Zhaofei, WU Jiequn, MENG Xiaolei, TANG Yue, WEI Yutuo, HUANG Ribo (*). Rational design of glycerol dehydratase: Swapping the genes encoding the subunits of glycerol dehydratase to improve enzymatic properties. Science Bulletin (Formerly, Chinese Science Bulletin), 2006, 51: 2977-2985. doi: 10.1007/s11434-006-2219-5.(SCI,JCR Q1,中科院一区, IF=11.78)

论著(章节):

[1] Co-Editor: Nanomaterials for Bio-Catalysis. Elsevier, 2021, Aug, ISBN: 9780128244364.

[2] Book Chapter: Applications of nano-biotechnology for sustainable water purification. In: industrial applications of nanomaterials. Elsevier, 2019, 08: 313-340. doi: 10.1016/B978-0-12-815749-7.00011-6.

[3] Book Chapter:Anaerobic digestion of microalgae biomass for methane production. In: Microalgae biotechnology for development of biofuel and wastewater treatment. Singapore: Springer, 2019, 05: 397–421. doi:10.1007/978-981-13-2264-8_16.

[4] Book Chapter:An overview on the application of ligninolytic microorganisms and enzymes for pretreatment of lignocellulosic biomass. In: Recent advancements in biofuels and bioenergy utilization. Singapore: Springer, 2018, 09: 53–72. doi: 10.1007/978-981-13-1307-3. (EI)

[5] Book Chapter: 海藻糖—21世纪的新型糖类(Trehalose : a novel sugar in the new century),2010,化学工程出版社.

[6] Book Chapter: 英汉对照分子生物学导论(An Introduction to Molecular Biology with Chinese Translation, Second Edition),2018, 化学工业出版社.

【科研项目】

主持国家重点研发计划课题、“863”子课题、NSFC国际合作、国家自然科学基金等国家级课题7项,主持省级、市厅级等课题10余项;获批国家级、省级大创等项目10余项。

目前主持或合作主持的主要国家与省部级科研项目:

[1] 国家重点研发计划课题(2017YFC1600806),食品微生物安全,主持;

[2] 国家自然科学基金项目(31972042):鲁氏酵母利用葡萄糖发酵合成D-阿拉伯糖醇的分子机制与代谢工程改造,主持;

[3] 国家自然科学基金国际合作项目(31950410550):Development of robust Lactobacillus reuteri cell factory for glycerol metabolism and biosynthesis of 3-hydroxypropionic acid through duel metabolic routes. 合作主持;

[4] 江苏省“六大人才高峰”高层次人才(SWYY-018):新型L-阿拉伯糖异构酶的制备与生物合成,主持;

[5] 中国博士后特别资助(2019T120402);新型固定化L-阿拉伯糖异构酶催化剂,外籍博士后合作导师;

[6] 中国博士后基金(2017M621657);L-阿拉伯糖异构酶展示与D-塔格糖的合成,外籍博士后合作导师;

[7] 中国博士后基金(2019M661759):进化新型酵母菌转化甘油生产D-阿拉伯糖醇及优化,外籍博士后合作导师;

[8] 中国博士后基金(2020M681510):甘蔗渣半纤维素水解残渣的厌氧降解特性及机理研究,博士后合作导师;

[9] 江苏省博士后基金(2020Z154):大米工业废水的工程菌群生物反应系统设计与PHAs的生产,外籍博士后合作导师;

近年结题的主要国家级科研项目:

[1]国家自然科学基金项目:酪酸梭菌1,3-丙二醇耐受性分子机制研究,主持;

[2]国家自然科学基金项目:宏基因组甘油脱水酶的分子催化机制及分子改造研究,主持;

[3] “863”项目子课题:新型固定化酶制备与生物合成,子课题主持;

[4] 国家自然科学基金合作项目: γ-PGA生物合成的代谢工程,校内主持;

[5] 国家“973”项目子任务:芽孢杆菌细胞工厂的基础研究,研究骨干;

[6] “973”项目子任务:嗜热厌氧细菌代谢改造及其纤维素酶的研究,研究骨干。

[7] “863”项目子课题:高温酸性α-淀粉酶的发酵工业技术,研究骨干;

【科研成果及奖励】

获江苏省级各类成果一等奖1项(2020)、二等奖2项(2017、2015);获江苏省优秀研究生毕业论文指导教师奖1项(2020);获市级二、三等奖各1项(2016、2013);获足球外围最靠谱的平台优秀教师(2020)、优秀研究导师(2020)、优秀研究生论文指导教师(2013-2020)等十余项荣誉称号。

【所获专利】

申请专利20余件, PCT 1项,第一发明人代表性专利:

[1] 一种木糖醇基因工程菌及其混合转化生产木糖醇的方法, 中国发明专利, 2015,ZL 201210209060.5.

[2] 一种1,3-丙二醇基因工程菌及转化生产1,3-丙二醇的方法, 中国发明专利, 2016,ZL 201410051175.5.

[3] 一株产D-阿拉伯糖醇的鲁氏酵母菌株及其应用, 中国发明专利, 201410337503.8.

[4] 一种全细胞混合转化甘油生产1,3-丙二醇的方法, 中国发明专利, 2020,ZL201810005295.X.

[5] 一种固定化酶催化剂生物合成D-塔格糖的方法, 中国发明专利,2020,ZL201711395868.6.

[6] 一种生产1,3-丙二醇用的酪酸梭菌菌株及其筛选方法和应用, 中国发明专利, 201910688714.9.

[7] 一种L-阿拉伯糖异构酶及其应用, 中国发明专利, 202010135941.1.

[8] 一种由乳清生产D-塔格糖的方法, 中国发明专利, 202010135919.7.

[9] 一种微生物利用甘油发酵生产1,3-丙二醇的方法. 中国发明专利, 202010212649.5.

[10] 一种高效联产3-羟基丙酸和1,3-丙二醇的多菌混合转化体系及建立方法. 中国发明专利, 202011046932.1.

[11] 一种联产3-羟基丙酸和1,3-丙二醇的基因工程菌及其构建方法和应用. 中国发明专利, 202011048794.0.

[12] 一种D塔格糖3差向异构酶DTE-CM及其构建方法和应用. 中国发明专利, 202011289022.6.

[13] 一种高效联产3-羟基丙酸和1,3-丙二醇的多菌混合转化体系及建立方法. PCT/CN2020/131691.

【在读硕、博士人数】

Prof.:翟彼得(Zabed);Lecturer: 赵梅(Mei Zhao);

PostDoc:潘世优(Psyou),赵梅(Mei Zhao),安润士(Amreesh),尤瓦(Yuvaraj),范迪(Fady),玛瑞安(Marian),易坤贝(Iqabl),瑞扎卡(Razack);

PhD Student:苏本(Saboor),员君华(Cherry),薛莉(Suely),李小兰(Fairy);欧大卫(David),张国艳(Iris),张宇飞(Fizz);

Postgraduate Student:黄嘉琦(Bessie),郭昊天(Steve),窦媛(Joanne),黄健(Haniel),王江飞(Jeff),马恩云(Yolanda),汤馨睿(Allen T);

Undergraduate student:段毅(Yi Duan), 宋松林(Songlin Song), 王京祎(Jingyi Wang),宋娟 (Juan Song),陈子斌(Zibin Chen),周海星(Haixing Zhou),丛宏日(Hongri Cong);

【已毕业硕、博士人数】

(1)王飞(Fei Wang,硕士,就业去向:北京);(2)邓文颖(Wing Deng,硕士,就业去向:南京);(3)罗艳(Yan Luo,硕士,就业去向:广州);(4)王旭(Xu Wang,硕士,就业去向:北京/瑞典);(5)朱婧斐(Jingfei Zhu,硕士,就业去向:中国医科院苏州所);(6)林静(Jing Lin,硕士,就业去向:南京);(7)张欢欢(Sunny,硕士,就业去向:博士);(8)田纳(Tina,硕士,就业去向:合肥);(9)杨苗苗(Amy,硕士,就业去向:上海药明康德);(10)员君华(Cherry,硕士,就业去向:博士);(11)张国艳(Iris,硕士,就业去向:博士);(12)翟彼得(Zabed, 博士后,就业去向:江大);(13)张宇飞(Fizz,硕士,就业去向:博士)(14)袁娇(Teixeira,硕士,就业去向:金丝瑞);(15)王洋(Alean W,硕士,就业去向:博士);(16)莫斯(Mostafa,博士后,就业去向:Tanta University);(17)胡克(Ernest,博士,就业去向:南京);(18)罗迪可(Radhika,博士后,就业去向:India);(19)鲍娜(Poorna,博士后,就业去向:India);

【指导本科生人数】

2-5人/年(学业导师)

【以上资料更新日期】

2021-7-18

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